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The Effect of Oral Glucose on Pain Relief in Newborns
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Hye Young Ahn, Me Young Jang, Myung Haeng Hur
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Journal of Korean Academy of Nursing 2006;36(6):992-1001. Published online March 28, 2017
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DOI: https://doi.org/10.4040/jkan.2006.36.6.992
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 Abstract
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Purpose
This study was done to provide data for a nursing intervention to alleviate newborn pain clinically by investigating the effect of oral glucose.
Purpose
Subjects were newborns hospitalized in the nursery. Informed consent was obtained from parents of 60 newborns. A heel stick was carried out for a test on 3 groups; the experimental, placebo, and control group. The Neonatal infant pain scale(NIPS), respiration rate, heart rate, peripheral oxygen partial pressure(SpO2), and crying duration were measured to assess pain reaction. All neonatal behaviors were recorded on videotape.
Purpose
There were significant differences in pain behavior during stimulus(F=4.195, p=.020), pain behavior immediately after blood-sampling (F=4.114, p=.021), and pain behavior 3 minutes after that (F=3.630, p=.033). However, there were no significant differences in heart rate, respiration rate, peripheral oxygen partial pressure or crying duration after the heel stick among the groups.
Conclusions
Oral administration of glucose before a heel stick caused the reduction of neonatal pain behavior, which means that it has an effect of pain relief.
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Citations
Citations to this article as recorded by  - A Bayesian network meta-analysis of non-pharmacological interventions for neonatal pain management: a clinical effectiveness comparison
Lingxue Xu, Lali Xiang, Lihui Pan, Peipei Xue, Juan Li, Yurong He, Hongyan Liu, Yuwei Hu, Bo Zheng
Frontiers in Pediatrics.2025;[Epub] CrossRef - Arnica D30 – an alternative for managing procedural pain in full-term neonates
Penka Petleshkova, Maya Krasteva, Iliyana Pacheva, Snezhana Dragusheva, Margarita Ruseva, Valentina Petkova, Kristina Kilova
Pharmacia.2024; 71: 1. CrossRef - The effect of oral breast milk on pain response of the neonates during heel lancing
Kyunghwa Kim, Youngim Park, Taeim Kim
Journal of the Korean Data and Information Science Society.2016; 27(1): 203. CrossRef - Effect of vapocoolant spray and EMLA cream upon DPT vaccination pain in infants
Gunja Jang, Eunyoung Jeon, Eunsil Lee
Journal of the Korean Data and Information Science Society.2014; 25(4): 705. CrossRef - Effects of Local Anesthetic Cream on Pain Relief in Newborns During Venipuncture
Hae-Won Kim, Hye-Young Ahn
Journal of Korean Academy of Child Health Nursing.2011; 17(4): 215. CrossRef - Factors Influencing Neonate Pain Management Performed by Nurses
In-Suk Noh, Jin-A Oh
Journal of Korean Academy of Child Health Nursing.2011; 17(3): 190. CrossRef - Pain Response to Procedural Pain in Premature Infants
Jung Sook Kim, Eun Jung Lee, Eun Ha Ham, Ji Hyun Kim, Young Hee Yi
Journal of Korean Academy of Child Health Nursing.2010; 16(4): 352. CrossRef
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