Abstract

• Purpose
  This study was done to provide data for a nursing intervention to alleviate newborn pain clinically by investigating the effect of oral glucose.
• Purpose
  Subjects were newborns hospitalized in the nursery. Informed consent was obtained from parents of 60 newborns. A heel stick was carried out for a test on 3 groups; the experimental, placebo, and control group. The Neonatal infant pain scale(NIPS), respiration rate, heart rate, peripheral oxygen partial pressure(SpO₂), and crying duration were measured to assess pain reaction. All neonatal behaviors were recorded on videotape.
• Purpose
  There were significant differences in pain behavior during stimulus(F=4.195, p=.020), pain behavior immediately after blood-sampling (F=4.114, p=.021), and pain behavior 3 minutes after that (F=3.630, p=.033). However, there were no significant differences in heart rate, respiration rate, peripheral oxygen partial pressure or crying duration after the heel stick among the groups.
• Conclusions
  Oral administration of glucose before a heel stick caused the reduction of neonatal pain behavior, which means that it has an effect of pain relief.
• Keywords: Newborn; Glucose; Pain; NIPS; Crying duration

Figure & Data

REFERENCES

Citations

Citations to this article as recorded by  

• A Bayesian network meta-analysis of non-pharmacological interventions for neonatal pain management: a clinical effectiveness comparison
  Lingxue Xu, Lali Xiang, Lihui Pan, Peipei Xue, Juan Li, Yurong He, Hongyan Liu, Yuwei Hu, Bo Zheng
  Frontiers in Pediatrics.2025;[Epub]     CrossRef
• Arnica D30 – an alternative for managing procedural pain in full-term neonates
  Penka Petleshkova, Maya Krasteva, Iliyana Pacheva, Snezhana Dragusheva, Margarita Ruseva, Valentina Petkova, Kristina Kilova
  Pharmacia.2024; 71: 1.     CrossRef
• The effect of oral breast milk on pain response of the neonates during heel lancing
  Kyunghwa Kim, Youngim Park, Taeim Kim
  Journal of the Korean Data and Information Science Society.2016; 27(1): 203.     CrossRef
• Effect of vapocoolant spray and EMLA cream upon DPT vaccination pain in infants
  Gunja Jang, Eunyoung Jeon, Eunsil Lee
  Journal of the Korean Data and Information Science Society.2014; 25(4): 705.     CrossRef
• Effects of Local Anesthetic Cream on Pain Relief in Newborns During Venipuncture
  Hae-Won Kim, Hye-Young Ahn
  Journal of Korean Academy of Child Health Nursing.2011; 17(4): 215.     CrossRef
• Factors Influencing Neonate Pain Management Performed by Nurses
  In-Suk Noh, Jin-A Oh
  Journal of Korean Academy of Child Health Nursing.2011; 17(3): 190.     CrossRef
• Pain Response to Procedural Pain in Premature Infants
  Jung Sook Kim, Eun Jung Lee, Eun Ha Ham, Ji Hyun Kim, Young Hee Yi
  Journal of Korean Academy of Child Health Nursing.2010; 16(4): 352.     CrossRef