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				Effect and Path Analysis of Laughter Therapy on Serotonin, Depression and Quality of Life in Middle-aged Women														
			
			Mi Youn Cha, Hae Sook Hong			
				J Korean Acad Nurs 2015;45(2):221-230.   Published online April 30, 2015			
									DOI: https://doi.org/10.4040/jkan.2015.45.2.221
							
							 
				
										
										 Abstract  PDF
Purpose
This study was done to examine how laughter therapy impacts serotonin levels, QOL and depression in middle-aged women and to perform a path analysis for verification of the effects.Methods A quasi-experimental study employing a nonequivalent control group and pre-post design was conducted. Participants were 64 middle-aged women (control=14 and experimental=50 in 3 groups according to level of depression). The intervention was conducted five times a week for a period of 2 weeks and the data analysis was conducted using repeated measures ANOVA, ANCOVA and LISREL.Results Results showed that pre serotonin and QOL in women with severe depression were the lowest. Serotonin in the experimental groups increased after the 10th intervention (p=.006) and the rise was the highest in the group with severe depression (p=.001). Depression in all groups decreased after the 5th intervention (p=.022) and the biggest decline was observed in group with severe depression (p=.007). QOL of the moderate and severe groups increased after the 10th intervention (p=.049), and the increase rate was highest in group with severe depression (p<.006). Path analysis revealed that laughter therapy did not directly affect depression, but its effect was indirectly meditated through serotonin variation (p<.001).Conclusion Results indicate that serotonin activation through laughter therapy can help middle-aged women by lessening depression and providing important grounds for depression control.
					Citations Citations to this article as recorded by   Effectiveness of yoga and laughter yoga in improving psychological resilience of mothers with babies hospitalized in neonatal intensive care unitZerrin Çiğdem, Emine Sarikamiş Kale, Tuba Koç Özkan
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The Effects of Comedy Movies on Preoperative Anxiety and Postoperative Pain in Patients Who Have Undergone Abdominal Surgery: A Pilot Randomized Controlled TrialGürkan Kapıkıran, Semra Bülbüloğlu, Remziye Cici
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The Effect of Laughter Yoga on Depression and Serotonin Levels in Patients Who Underwent Bariatric SurgeryGülnaz Kızılkaya, Meral Özkan
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Laughter Interventions to Improve Psychological Well-Being/QoL in Cancer Patients: A Mini Systematic ReviewAnastasia Olympiou, Sana Ahmed
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Development of an Artificial Intelligence–Based Tailored Mobile Intervention for Nurse Burnout: Single-Arm TrialAram Cho, Chiyoung Cha, Gumhee Baek
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 Belitung Nursing Journal.2019; 5(6): 246.     CrossRef
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 Korean Journal of Adult Nursing.2017; 29(5): 560.     CrossRef
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A Systematic Review of Non-pharmacological Intervention for Depression in Korean Middle-aged WomenMyung-Ock Chae, Hae Ok Jeon, Ahrin Kim
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Yoga and physical exercise – a review and comparisonRamajayam Govindaraj, Sneha Karmani, Shivarama Varambally, B.N. Gangadhar
 International Review of Psychiatry.2016; 28(3): 242.     CrossRef
Therapeutic Benefits of Laughter in Mental Health: A Theoretical ReviewJongEun Yim
 The Tohoku Journal of Experimental Medicine.2016; 239(3): 243.     CrossRef
Effects of Laughter Therapy on Immune Responses in Postpartum WomenKyung Hee Ryu, Hye Sook Shin, Eun Young Yang
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				Transmission Aspect of Methicillin-resistant Staphylococcus aureus in the Neurosurgical Intensive Care Unit by Analysing Genotype														
			
			Yun Kyung Kim, Hae Sook Hong			
				Journal of Korean Academy of Nursing 2007;37(6):976-985.   Published online March 28, 2017			
									DOI: https://doi.org/10.4040/jkan.2007.37.6.976
							
							 
				
										
										 Abstract  PDF
 PURPOSE: The aim of this study was to identify the present situation of hospital infection and route of infection by clarifying the transmission aspect of methicillin-resistant Staphylococcus aureus(MRSA) in a Neurosurgical Intensive Care Unit by analysing genotype.
 METHODS: MRSA was cultured from twenty five patients with a tracheostomy, twenty five health care workers, and environments in the Neurosurgical Intensive Care Unit of one hospital in D city. Data was collected from December 21, 2004 to November 5, 2005. MRSA isolates representing each genotype were analyzed by spaA typing and a multiplex PCR method capable of identifying the structural type of the staphylococcal cassette chromosome mec(SCCmec) carried by the bacteria.
 RESULTS: As the same genotype and gene sequence were found among health care workers, patients, and environments, it was assumed that there was cross transmission among them.
 CONCLUSION: This study suggests that first, as the hospital infection by MRSA between health care workers and patients in the Neurosurgical Intensive Care Unit was due to result of cross transmission and the relevance of transmission between them was verified, it is necessary to take preventive measures and conduct education. Secondly, development of nursing interventions and study of infection are needed. Thirdly, consistent investment in prevention against hospital infections and environmental renovation is needed.
					Citations Citations to this article as recorded by   A Comparison between the Contamination Level of Uniforms and the Nasal Staphylococcus aureus Colonization before and after the Clinical Practice of Nursing StudentsJin Hee Park, Gisoo Shin, Jiyoung Kim
 Journal of Korean Biological Nursing Science.2014; 16(2): 90.     CrossRef
The Effect of the Hand Hygiene Education Program on Hand Hygiene Knowledge, Hand Hygiene Perception, Nasal Staphylococcus aureus Colonization and Hand Hygiene Adherence in Nursing StudentsJin Hee Park, Hee Sun Kim
 Journal of Korean Biological Nursing Science.2012; 14(3): 156.     CrossRef
 
		
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				The Effects of the Ulmus Root-bark Dressing in Tissue Regeneration of Induced Pressure Ulcers in Rats														
			
			Yeon Kyung Na, Hae Sook Hong			
				Journal of Korean Academy of Nursing 2006;36(3):523-531.   Published online June 30, 2006			
									DOI: https://doi.org/10.4040/jkan.2006.36.3.523
							
							 
				
										
										 Abstract  PDF
Purpose
  The purpose of this study was to examine the effects of the ulmus root-bark dressing on tissue regeneration in experimentally-induced pressure ulcers in rats.Method A randomized pretest/post-test control group time-series study design was used. Thirty-three male Sprague-Dawley rats were used in this study. The rats were anesthetized with 100mg/kg of ketamine. Pressure ulcers were induced at 140mmHg for three hours using a personally-designed pressing apparatus. For four weeks, the ulmus root-bark dressing was applied every other day in the experimental group (n=18) and a wet gauze dressing in the control group (n=15). For data analysis, the statistical program SPSS WIN 12 was used. The wounds were examined by light microscopy and electron microscopy.Result There were significant statistical differences in the size of the pressure ulcers as time went by(p=0.006). It should be noted that there were no significant statistical differences in the number of capillaries. Using light microscopy the inflammatory infiltration and neovascularization in the dermis in the experimental group emerged densely in the early stages, but recovered rapidly at the latter stages. In addition, the reepithelization of the epidermis occurred earlier than in the control group. By electron microscopy, the cell organelles of the capillary endothelial cells and the basal lamina of capillaries in the experimental group showed a more rapid maturation during the latter stages, compared with the control group.Conclusion According to this study, it can be concluded that the ulmus root-bark dressing is effective regarding the healing of pressure ulcers.
					Citations Citations to this article as recorded by   Use of Animals for Nursing Research in KoreaHae Young Yoo
 Journal of Korean Biological Nursing Science.2015; 17(4): 324.     CrossRef
The Effect of Ulmus Root-bark Dressing in Fibroblast Growth Factor and Vascular Endothelial Growth Factor of Induced Pressure Ulcer in RatsYeon Kyung Na
 Journal of Korean Biological Nursing Science.2013; 15(4): 257.     CrossRef
Factors Affecting the Healing of Pressure Ulcers in a Korean Acute Care HospitalYoung Hee Sung, Kyung Hee Park
 Journal of Wound, Ostomy & Continence Nursing.2011; 38(1): 38.     CrossRef
 
		
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