Seung-Ae Park; Jong-Kyung Kim

doi:10.4040/jkan.2011.41.2.191

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Original Article
Estrogen Attenuates the Pressor Response Mediated by the Group III Mechanoreflex: Seung-Ae Park, Jong-Kyung Kim; Journal of Korean Academy of Nursing 2011;41(2):191-196.
DOI: https://doi.org/10.4040/jkan.2011.41.2.191
Published online: April 30, 2011

¹Doctoral Student, Graduate School of Physical Education, Kyung Hee University, Yongin, Korea.

²Assistant Professor, Graduate School of Physical Education, Kyung Hee University, Yongin, Korea.

Address reprint requests to: Kim, Jong-Kyung. Graduate School of Physical Education, Kyung Hee University, 1 Seocheon-dong, Giheung-gu, Yongin 446-701, Korea. Tel: +82-31-201-2778, Fax: +82-31-201-3743, kyung19692002@khu.ac.kr

• Received: September 4, 2010 • Accepted: April 15, 2011

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Abstract
NOTES
NOTES
REFERENCES

Abstract

Purpose
We investigated the effects of group III mechanoreceptors to cardiovascular responses in both pre-menopausal woman and post-menopausal woman during passive ankle dorsiflexion (PAD).
Methods
Twenty healthy volunteers (10 post-menopausal women and 10 pre-menopausal women) were recruited for this study. Stroke volume (SV), heart rate (HR), cardiac output (CO), and total vascular conductances (TVC) were measured continuously throughout the experiment. To stimulate the group III mechanoreceptors, PAD was performed for one minute.
Results
The results showed that mean arterial pressure (MAP) mediated by the mechanoreflex activation was significantly increased in both groups. However, this pressor response was significantly higher in post-menopausal women. This reflex significantly increased both SV and CO in pre-menopausal women, while there were no differences in post-menopausal women. There was no difference in HR in either group. The mechanoreflex significantly decreased TVC in post-menopausal woman, while there was no difference in pre-menopausal woman.
Conclusion
The results indicate that the excessive pressor response mediated by the mechanoreflex occurs due to overactivity of group III mechanorecptors and the mechanism is produced mainly via peripheral vasoconstriction in post-menopausal women.
Keywords: Estrogen; Post-menopausal woman; Exercise pressor reflex; Group III mechanoreceptors; Cardiac output

This study is a thesis of master of science.

This work was supported by a grant from Kyung Hee University in 2006 (KHU-20061278).

REFERENCES

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Figure 1

Experimental foot ankle dorsiflexion

Figure 2

Cardiovascular responses mediated by the mechanorefelx during foot ankle dorsiflexion.

Values are mean±standard error. PMW=Premenopausal woman; PTW=Postmenopausal woman; Black Bar: baseline; Gray Bar: mechanoreflex activation. ^*Significantly different from baseline value, p<.05; #Significantly different from PMW, p<.05; MAP=mean arterial pressure; HR=heart rate; SV=stroke volume; CO cardiac output; TVC=total vascular conductances.

Table 1

Physical Characteristics of Participants

Values are mean±standard error.

^*p<.05 vs. PMW.

PMW=premenopausal woman; PTW=postmenopausal woman; SBP=systolic blood pressure; DBP=diastolic blood pressure.

Figure & Data

REFERENCES

Citations

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Estrogen Attenuates the Pressor Response Mediated by the Group III Mechanoreflex

J Korean Acad Nurs. 2011;41(2):191-196. Published online April 30, 2011

DOI: https://doi.org/10.4040/jkan.2011.41.2.191

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Figure

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Estrogen Attenuates the Pressor Response Mediated by the Group III Mechanoreflex

Figure 1 Experimental foot ankle dorsiflexion

Figure 2 Cardiovascular responses mediated by the mechanorefelx during foot ankle dorsiflexion. Values are mean±standard error. PMW=Premenopausal woman; PTW=Postmenopausal woman; Black Bar: baseline; Gray Bar: mechanoreflex activation. *Significantly different from baseline value, p<.05; #Significantly different from PMW, p<.05; MAP=mean arterial pressure; HR=heart rate; SV=stroke volume; CO cardiac output; TVC=total vascular conductances.

Figure 1

Figure 2

Estrogen Attenuates the Pressor Response Mediated by the Group III Mechanoreflex

Table 1

Physical Characteristics of Participants

Values are mean±standard error.

^*p<.05 vs. PMW.

PMW=premenopausal woman; PTW=postmenopausal woman; SBP=systolic blood pressure; DBP=diastolic blood pressure.

Table 1 Physical Characteristics of Participants

Values are mean±standard error.

^*p<.05 vs. PMW.

PMW=premenopausal woman; PTW=postmenopausal woman; SBP=systolic blood pressure; DBP=diastolic blood pressure.