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Analysis of ROX Index, ROX-HR Index, and SpO 2 /FIO 2 Ratio in Patients Who Received HighFlow Nasal Cannula Oxygen Therapy in Pediatric Intensive Care Unit
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Sun Hee Choi, Dong Yeon Kim, Byung Yun Song, Yang Sook Yoo
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J Korean Acad Nurs 2023;53(4):468-479. Published online August 31, 2023
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DOI: https://doi.org/10.4040/jkan.22152
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Abstract
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This study aimed to evaluate the use of the respiratory rate oxygenation (ROX) index, ROX-heart rate (ROX-HR) index, and saturation of percutaneous oxygen/fraction of inspired oxygen ratio (SF ratio) to predict weaning from high-flow nasal cannula (HFNC) in patients with respiratory distress in a pediatric intensive care unit. Methods A total of 107 children admitted to the pediatric intensive care unit were enrolled in the study between January 1, 2017, and December 31, 2021. Data on clinical and personal information, ROX index, ROX-HR index, and SF ratio were collected from nursing records. The data were analyzed using an independent t-test, χ2 test, Mann–Whitney U test, and area under the curve (AUC). Results Seventy-five (70.1%) patients were successfully weaned from HFNC, while 32 (29.9%) failed. Considering specificity and sensitivity, the optimal cut off points for predicting treatment success and failure of HFNC oxygen therapy were 6.88 and 10.16 (ROX index), 5.23 and 8.61 (ROX-HR index), and 198.75 and 353.15 (SF ratio), respectively. The measurement of time showed that the most significant AUC was 1 hour before HFNC interruption. Conclusion The ROX index, ROX-HR index, and SF ratio appear to be promising tools for the early prediction of treatment success or failure in patients initiated on HFNC for acute hypoxemic respiratory failure. Nurses caring for critically ill pediatric patients should closely observe and periodically check their breathing patterns. It is important to continuously monitor three indexes to ensure that ventilation assistance therapy is started at the right time.
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Citations
Citations to this article as recorded by 
- Non-invasive SpO2/FiO2 ratio (SFR) as surrogate for PaO2/FiO2 ratio (PFR): A scoping review
Madhura Reddy, Malavika Kulkarni, Sushma Thimmaiah Kanakalakshmi, Laxmi Shenoy, Rama Rani KrishnaBhat The Journal of Critical Care Medicine.2025; 11(3): 221. CrossRef - Can the ROX index predict high‐flow nasal cannula failure in children under 2 with lower respiratory tract infection?
Pablo Vasquez‐Hoyos, Alvaro L. Jacome‐Orozco, Andrea P. Rodriguez‐Mayorga, Leidy E. Sepulveda‐Forero, Diana P. Escobar‐Serna, Juan S. Barajas, Evelyn Obando‐Belalcazar, Claudia M. Salinas‐Jaimes, Juan J. Peralta‐Palmezano, Alexandra Jimenez‐Chavez, Rafael Pediatric Pulmonology.2024; 59(5): 1246. CrossRef - Impact of Surgical Mask Placement Over High-Flow Nasal Cannula on Oxygenation Parameters in COVID-19 Patients Experiencing Hypoxemic Respiratory Failure
Aadila Coatwala, Mayank Dhir, Sagar Sinha, Dattatray Bhusare Cureus.2024;[Epub] CrossRef
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Late Effects, Social Adjustment, and Quality of Life in Adolescent Survivors of Childhood Leukemia
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Sung Sil Hong, Ho Ran Park, Kwang Sung Kim, Sun Hee Choi
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J Korean Acad Nurs 2014;44(1):55-63. Published online February 28, 2014
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DOI: https://doi.org/10.4040/jkan.2014.44.1.55
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Abstract
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Purpose
This study was conducted to examine the late effects, social adjustment, and quality of life in adolescents who had been completely treated for childhood leukemia and their parents.
Methods
Participants consisted of 41 pairs of adolescent survivors (13-18 years) and their parents. Parents checked for their child's physical late effects. The Korean Version of Post-Traumatic Symptoms for psychological late effects, social functioning questionnaire for social adjustment and the PedsQL 4.0 Generic Core Scales for quality of life were completed by adolescents and parents. Data were analyzed using SPSS.
Results
Twenty out of 41 adolescents had one or more physical late effects. Adolescents showed more serious psychological late effect than parents. Five children and seven parents had above cut-off scores and they were considered the high risk group for posttraumatic symptoms. Parent-reported scores were significantly higher than child-reported scores in terms of social adjustment and emotional functioning of quality of life. Low school functioning in adolescents was associated with physical late effects.
Conclusion
The results indicate that long-term and systematic management for childhood leukemia survivors affect positive social adjustment and can further improve quality of life.
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Citations
Citations to this article as recorded by 
- An Integrated Review of Health Care in Child and Adolescent Cancer Survivors Based on Roy’s Adaptation Model
Hye Jin Kim, Eunjoo Lee Asian Oncology Nursing.2024; 24(2): 82. CrossRef - Technology-based psychosocial support for adolescent survivors of leukemia
Tuba ARPACI, Naime ALTAY Journal of Integrative Nursing.2022; 4(3): 157. CrossRef - Self-efficacy, post-traumatic growth, and quality of life of pediatric cancer survivors: A cross-sectional study
Yeunhee Kwak, Yoonjung Kim, Eun Seok Choi, Ho Joon Im European Journal of Oncology Nursing.2021; 54: 102019. CrossRef - Difficulty in returning to school among adolescent leukemia survivors: A qualitative descriptive study
Hyeran An, Sunhee Lee European Journal of Oncology Nursing.2019; 38: 70. CrossRef - Sleep Pattern and Factors Causing Sleep Disturbance in Adolescents with Cancer before and after Hospital Admission
Jin Jung, Eun-Hye Lee, You-Jin Yang, Bo-Yoon Jang Asian Oncology Nursing.2017; 17(3): 143. CrossRef - Qualitative Evaluation of Effectiveness of ‘Family Hope Partner Project’ for Pediatric Cancer Patients and their Families
김선희 Korean Journal of Family Social Work.2017; null(55): 59. CrossRef - The Experiences of Korean Young Adult Survivors of Childhood Cancer
Jaehee Yi, Min Ah Kim, Sangmin An Qualitative Health Research.2016; 26(8): 1044. CrossRef - The Effect of Perceived Social Stigma on Self-Esteem of Childhood Cancer Survivors
김민아, 남석인, 장은혜, Lee Daji Health and Social Welfare Review.2016; 36(1): 497. CrossRef - Health-related Needs and Quality of Life in Childhood Cancer Survivors
Su-Jin Lim Asian Oncology Nursing.2015; 15(4): 246. CrossRef
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